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Donepezil

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Basic Medical Informatin
Treatment For Mild To Moderate Dementia Caused By Alzheimer's Disease 
Legal Status Rx-only 
Pregnancy cat. C (US)  
Possible Side Effects Nausea, Diarrhea, Vomiting, Muscle Cramps, Fatigue And Loss Of Appetite, Headache, Fatigue 
Precautions & Contraindications Heart Disease, Stomach Problems, Liver Or Kidney Disease, Breathing Problems, Urinary Obstruction, Brain Tumor, Head Injury, Seizures, Copd, And Pregnancy And Breastfeeding. 
Excretion 0,11-0,13 (l/h/kg) 
Storage Conditions 15° To 30°c, In An Airtight Container 
Dosage, Usage and Forms
Forms Tablet 
Routes (of administration) Oral 
Dosage
5 mg (68.82 mg lower than average)
vs
73.82 mg

Chemical Data
Bioavailability
100 % (18.38 % higher than average)
vs
81.62 %

Protein binding
96 % (20.83 % higher than average)
vs
75.17 %

Metabolism Hepatic 
Half Life (hours)
70 h (36.7 h higher than average)
vs
33.30 h

Formula C24H29NO3  
Molecular mass (g/mol) 379.492 G/mol 


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