| Basic Medical Informatin |
| brand name |
| Tegretol |
Zoloft |
| Treatment For |
| Seizures And Nerve Pain Such As Trigeminal Neuralgia And Diabetic Neuropathy |
Depression, Obsessive-compulsive Disorder, Panic Disorder, Anxiety Disorders, Post-traumatic Stress Disorder (ptsd), And Premenstrual Dysphoric Disorder (pmdd) |
| Legal Status |
| Rx-only |
Rx-only |
| Pregnancy cat. |
| D (us) |
C (us) |
| Possible Side Effects |
| Dizziness, Drowsiness, Unsteadiness, Nausea And Vomiting |
Fever, Sweating, Confusion, Fast Or Uneven Heartbeats, Agitation, Hallucinations, Fever, Overactive Reflexes, Tremors, Nausea, Vomiting, Diarrhea, Loss Of Appetite, Feeling Unsteady, Loss Of Coordination, Or Headache, Trouble Concentrating, Memory Problems, Weakness, Fainting, Seizure, Shallow Breathing |
| Precautions & Contraindications |
| Increased Eye Pressure, Psychosis, Heart, Kidney, Thyroid Or Liver Diseases, Mood Or Mental Problems, Suicidal Thoughts, Seizures, Pregnancy And Breastfeeding |
Hypomania And Seizure Disorders, Liver Or Kidney Damage, Heart Disease, Recent Heart Attack, Bleeding Disorders, Diabetes And Angle-closure Glaucoma |
| Excretion |
| 2–3% Excreted Unchanged In Urine |
Renal |
| Storage Conditions |
| Room Temperature |
15-30°c |
|
| Dosage, Usage and Forms |
| Forms |
| Tablet |
Tablet |
| Routes (of administration) |
| Oral |
Oral |
|
Dosage |
| 200 mg |
50 mg |
| Chemical Data |
| Bioavailability |
| 80 % |
44 % |
| Protein binding |
| 76 % |
99 % |
| Metabolism |
| Hepatic |
Hepatic |
| Half Life (hours) |
| 25-65 H (after Several Doses 12-17 H) |
Approximately 26 H |
| Formula |
| C15h12n2o |
C17h17cl2n |
| Molecular mass (g/mol) |
| 236.269 G/mol |
306.229 G/mol |