| Basic Medical Informatin |
| brand name |
| Exelon, Exelon Td, Rivastigmine Td |
Depakote |
| Treatment For |
| Mild To Moderate Dementia Caused By Alzheimer's Or Parkinson's Disease |
Various Types Of Seizure Disorders, Epilepsy |
| Legal Status |
| Rx-only |
Rx-only |
| Pregnancy cat. |
| B (us) |
D (us) |
| Possible Side Effects |
| Vomiting Or Diarrhea, Loss Of Appetite, Weight Loss; Dry Mouth, Unable To Urinate, Heavy Sweating, Or Hot And Dry Skin; Black Or Bloody Stools, Coughing Up Blood Or Vomit; Restless Muscle Movements In Your Eyes, Tongue, Jaw, Or Neck; Tremors (uncontrolled Shaking); Seizure (convulsions); Headache, Tired Feeling; Dizziness, Spinning Feeling; Anxiety, Depressed Mood; Mild Nausea Or Stomach Pain; Muscle Weakness; Sleep Problems (insomnia); Skin Redness |
Weakness, Nausea And Vomiting, Diarrhea, Stomach Pain, Headache, Indigestion, Loss Of Appetite, Shaking Hands, Sleepiness Or Sleeplessness, Dizziness, Forgetfulness, Respiratory Infections, And Hair Loss |
| Precautions & Contraindications |
| Liver Or Kidney Disease; Recent Weight Loss Or Lack Of Appetite; A Heart Rhythm Disorder Such As "sick Sinus Syndrome" (slow Heartbeats); An Enlarged Prostate Or Urination Problems; Epilepsy Or Other Seizure Disorder; Asthma Or Other Breathng Disorder; A History Of Stomach Ulcer; Tremors (dyskinesia) Or Uncontrolled Muscle Movements. |
Brain, Liver, Kidney Problems, Metabolic Disease, Blood Disease, Decrease In Albumin, Hiv Infection, Pregnancy And Breastfeeding |
| Excretion |
| Renal, 97% |
|
| Storage Conditions |
| Room Temperature And In An Airtight Container |
15-30°c |
|
| Dosage, Usage and Forms |
| Forms |
|
Tablet |
| Routes (of administration) |
| Oral, Transdermal |
Oral |
|
Dosage |
| 6 (6-12 mg (Exelon), 1.5 mg (Rivastigmine TD)) |
250 mg |
| Chemical Data |
| Bioavailability |
| 96 % |
90 % |
| Protein binding |
| 40 % |
|
| Metabolism |
| Hepatic, Via Pseudocholinesterase |
Liver |
| Half Life (hours) |
| 1.5 h |
8-15 H |
| Formula |
| C14h22n2o2 |
C16h31nao4 |
| Molecular mass (g/mol) |
| 250.337 G/mol |
310.405 G/mol |