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Overview:

There are 15 differences and 2 similarities between Donepezil, Rivastigmine

Basic Medical Informatin
brand name		Aricept, Aricept Odt	vs	Exelon, Exelon Td, Rivastigmine Td
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Treatment For		Mild To Moderate Dementia Caused By Alzheimer's Disease	vs	Mild To Moderate Dementia Caused By Alzheimer's Or Parkinson's Disease
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Legal Status		Rx-only	vs	Rx-only
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Pregnancy cat.		C (us)	vs	B (us)
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Possible Side Effects		Nausea, Diarrhea, Vomiting, Muscle Cramps, Fatigue And Loss Of Appetite, Headache, Fatigue	vs	Vomiting Or Diarrhea, Loss Of Appetite, Weight Loss; Dry Mouth, Unable To Urinate, Heavy Sweating, Or Hot And Dry Skin; Black Or Bloody Stools, Coughing Up Blood Or Vomit; Restless Muscle Movements In Your Eyes, Tongue, Jaw, Or Neck; Tremors (uncontrolled Shaking); Seizure (convulsions); Headache, Tired Feeling; Dizziness, Spinning Feeling; Anxiety, Depressed Mood; Mild Nausea Or Stomach Pain; Muscle Weakness; Sleep Problems (insomnia); Skin Redness
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Precautions & Contraindications		Heart Disease, Stomach Problems, Liver Or Kidney Disease, Breathing Problems, Urinary Obstruction, Brain Tumor, Head Injury, Seizures, Copd, And Pregnancy And Breastfeeding.	vs	Liver Or Kidney Disease; Recent Weight Loss Or Lack Of Appetite; A Heart Rhythm Disorder Such As "sick Sinus Syndrome" (slow Heartbeats); An Enlarged Prostate Or Urination Problems; Epilepsy Or Other Seizure Disorder; Asthma Or Other Breathng Disorder; A History Of Stomach Ulcer; Tremors (dyskinesia) Or Uncontrolled Muscle Movements.
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Excretion		0,11-0,13 (l/h/kg)	vs	Renal, 97%
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Storage Conditions		15° To 30°c, In An Airtight Container	vs	Room Temperature And In An Airtight Container
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Dosage, Usage and Forms
Forms		Tablet	vs
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Routes (of administration)		Oral	vs	Oral, Transdermal
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Dosage		5 mg	vs	6 (6-12 mg (Exelon), 1.5 mg (Rivastigmine TD))
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Chemical Data
Bioavailability		100 %	vs	96 %
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Protein binding		96 %	vs	40 %
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Metabolism		Hepatic	vs	Hepatic, Via Pseudocholinesterase
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Half Life (hours)		70 h	vs	1.5 h
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Formula		C24h29no3	vs	C14h22n2o2
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Molecular mass (g/mol)		379.492 G/mol	vs	250.337 G/mol
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Compare Donepezil vs Rivastigmine Alzheimer's Medications

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