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Rivastigmine

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Rivastigmine VS
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Basic Medical Informatin
Treatment For Mild To Moderate Dementia Caused By Alzheimer's Or Parkinson's Disease 
Legal Status Rx-only 
Pregnancy cat. B (US)  
Possible Side Effects Vomiting Or Diarrhea, Loss Of Appetite, Weight Loss; Dry Mouth, Unable To Urinate, Heavy Sweating, Or Hot And Dry Skin; Black Or Bloody Stools, Coughing Up Blood Or Vomit; Restless Muscle Movements In Your Eyes, Tongue, Jaw, Or Neck; Tremors (uncontrolled Shaking); Seizure (convulsions); Headache, Tired Feeling; Dizziness, Spinning Feeling; Anxiety, Depressed Mood; Mild Nausea Or Stomach Pain; Muscle Weakness; Sleep Problems (insomnia); Skin Redness 
Precautions & Contraindications Liver Or Kidney Disease; Recent Weight Loss Or Lack Of Appetite; A Heart Rhythm Disorder Such As "sick Sinus Syndrome" (slow Heartbeats); An Enlarged Prostate Or Urination Problems; Epilepsy Or Other Seizure Disorder; Asthma Or Other Breathng Disorder; A History Of Stomach Ulcer; Tremors (dyskinesia) Or Uncontrolled Muscle Movements. 
Excretion Renal, 97% 
Storage Conditions Room Temperature And In An Airtight Container 
Dosage, Usage and Forms
Routes (of administration) Oral, Transdermal 
Dosage
6 (6-12 mg (Exelon), 1.5 mg (Rivastigmine TD)) (67.82 lower than average)
vs
73.82 (6-12 mg

Chemical Data
Bioavailability
96 % (14.38 % higher than average)
vs
81.62 %

Protein binding
40 % (35.17 % lower than average)
vs
75.17 %

Metabolism Hepatic, Via Pseudocholinesterase 
Half Life (hours)
1.5 h (31.8 h lower than average)
vs
33.30 h

Formula C14H22N2O2  
Molecular mass (g/mol) 250.337 G/mol 


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