Compare with other Alzheimer's Medications
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Rivastigmine | VS | All other Alzheimer's Medications |
Basic Medical Informatin | |||||
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Treatment For | Mild To Moderate Dementia Caused By Alzheimer's Or Parkinson's Disease | ||||
Legal Status | Rx-only | ||||
Pregnancy cat. | B (US) | ||||
Possible Side Effects | Vomiting Or Diarrhea, Loss Of Appetite, Weight Loss; Dry Mouth, Unable To Urinate, Heavy Sweating, Or Hot And Dry Skin; Black Or Bloody Stools, Coughing Up Blood Or Vomit; Restless Muscle Movements In Your Eyes, Tongue, Jaw, Or Neck; Tremors (uncontrolled Shaking); Seizure (convulsions); Headache, Tired Feeling; Dizziness, Spinning Feeling; Anxiety, Depressed Mood; Mild Nausea Or Stomach Pain; Muscle Weakness; Sleep Problems (insomnia); Skin Redness | ||||
Precautions & Contraindications | Liver Or Kidney Disease; Recent Weight Loss Or Lack Of Appetite; A Heart Rhythm Disorder Such As "sick Sinus Syndrome" (slow Heartbeats); An Enlarged Prostate Or Urination Problems; Epilepsy Or Other Seizure Disorder; Asthma Or Other Breathng Disorder; A History Of Stomach Ulcer; Tremors (dyskinesia) Or Uncontrolled Muscle Movements. | ||||
Excretion | Renal, 97% | ||||
Storage Conditions | Room Temperature And In An Airtight Container |
Dosage, Usage and Forms | |||||
---|---|---|---|---|---|
Routes (of administration) | Oral, Transdermal | ||||
Dosage |
6 (6-12 mg (Exelon), 1.5 mg (Rivastigmine TD)) (67.82 lower than average)
|
vs |
73.82 (6-12 mg
|
Chemical Data | |||||
---|---|---|---|---|---|
Bioavailability |
96 % (14.38 % higher than average)
|
vs |
81.62 %
|
||
Protein binding |
40 % (35.17 % lower than average)
|
vs |
75.17 %
|
||
Metabolism | Hepatic, Via Pseudocholinesterase | ||||
Half Life (hours) |
1.5 h (31.8 h lower than average)
|
vs |
33.30 h
|
||
Formula | C14H22N2O2 | ||||
Molecular mass (g/mol) | 250.337 G/mol |