Tacrine Alternatives
Tacrine
- Dosage: 10
- Routes (of administration): Oral, Rectal
- Bioavailability: 24-36%
- Protein binding: 55
- Metabolism: Hepatic
- Half Life (hours): 2.9-3.6 h
- Formula: C13H14N2
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- Sertraline
- Dosage: 50
- Routes (of administration): Oral
- Bioavailability: 44
- Protein binding: 99
- Metabolism: Hepatic
- Half Life (hours): Approximately 26 h
- Formula: C17H17Cl2N
- Donepezil
- Dosage: 5
- Routes (of administration): Oral
- Bioavailability: 100
- Protein binding: 96
- Metabolism: Hepatic
- Half Life (hours): 70
- Formula: C24H29NO3
- Citalopram
- Dosage: 20
- Routes (of administration): Oral
- Bioavailability: 80%, peak at 4 hours
- Metabolism: Hepatic
- Half Life (hours): 35
- Formula: C20H21FN2O
- Carbamazepine
- Dosage: 200
- Routes (of administration): Oral
- Bioavailability: 80
- Protein binding: 76
- Metabolism: Hepatic
- Half Life (hours): 25-65 h (after several doses 12-17 h)
- Formula: C15H12N2O
- Ethosuximide
- Dosage: 250
- Routes (of administration): Oral
- Bioavailability: 93
- Protein binding: Hepatic
- Metabolism: Hepatic
- Half Life (hours): 53
- Formula: C7H11NO2
- Memantine
- Dosage: 5
- Routes (of administration): Oral
- Bioavailability: 100
- Protein binding: Hepatic (<10%)
- Half Life (hours): 60-100 h
- Formula: C12H21N
- Mirtazepine
- Dosage: 15
- Routes (of administration): Oral
- Bioavailability: 50
- Protein binding: 85
- Metabolism: Liver
- Half Life (hours): 20-40 h
- Formula: C17H19N3
- Sodium valproate
- Dosage: 250
- Routes (of administration): Oral
- Bioavailability: 90
- Metabolism: Liver
- Half Life (hours): 8-15 h
- Formula: C16H31NaO4